Photo by Sarah Mack

Search Santiago Island hotels

  • Plan, book, stay with confidence

    • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Check Santiago Island hotel prices

Tonight
26 Dec - 27 Dec
Tomorrow night
27 Dec - 28 Dec
This weekend
27 Dec - 29 Dec
Next weekend
3 Jan - 5 Jan

Filter by

Guest rating
Guest rating
Property class

Top hotels and accommodation in Santiago Island

Hotel Galapagos Tortuga Bay
Outdoor pool

Hotel Galapagos Tortuga Bay

2.0 star property
8.0 out of 10, Very good, (4)
"Nono"
The price is AU$205
includes taxes & fees
9 Jan - 10 Jan 2025
Hotel Galapagos Tortuga Bay
Semilla Verde Boutique Hotel
Yoga

Semilla Verde Boutique Hotel

3.5 star property
9.8 out of 10, Exceptional, (55)
"Semila Verde Hotel on the edge of Santa Cruz Island in the Galapagos is a stunning and serene retreat. The property is beautifully maintained, and it's a unique experience to see giant turtles wandering freely around the grounds. The hotel offers delicious local dishes that truly capture the flavors of the region. The staff were incredibly friendly and went above and beyond, arranging all transportation to and from the airport and the city, making the stay seamless. It was a wonderful...
The price is AU$432
includes taxes & fees
27 Dec - 28 Dec
Semilla Verde Boutique Hotel
Twin Hotel Galapagos
Hiking

Twin Hotel Galapagos

3.0 star property
8.4 out of 10, Very good, (37)
"Se lo recomendaría a cualquiera que venga a Ecuador por primera vez. Después de disfrutar de Puerto Aoya en las Galápagos, se puede entrar en contacto con la vida de los lugareños en el restaurante y supermercado Bellavista. El hotel se encuentra en un lugar tranquilo y relajante. Para llegar a Puerto Aoya, recomendamos alquilar una bicicleta y coger el autobús de vuelta al túnel por 50¢. El personal es amable."
The price is AU$183
includes taxes & fees
6 Jan - 7 Jan 2025
Twin Hotel Galapagos
Natura Gardens Galápagos Hotel
Outdoor pool

Natura Gardens Galápagos Hotel

3.0 star property
5.6 out of 10, (4)
"Highland area which is colder. The town area is better for food option and transportation. However the staff is very helpful."
The price is AU$204
includes taxes & fees
27 Dec - 28 Dec
Natura Gardens Galápagos Hotel
Suymar Ecolodge Galapagos
Exterior detail

Suymar Ecolodge Galapagos

3.0 star property
8.8 out of 10, Excellent, (13)
"Family running the hotel were very nice and it’s in a nice quiet area. The hotel owner can drop you off/pick you up at Puerto Ayora and from the boat pier. "
The price is AU$208
includes taxes & fees
27 Dec - 28 Dec
Suymar Ecolodge Galapagos
Espectacular Private Villa with Unbeatable Views
Smart TV, stereo

Espectacular Private Villa with Unbeatable Views

9.6 out of 10, Exceptional, (8)
"second time , we love Casa Roca - cant wait to return"
Espectacular Private Villa with Unbeatable Views
Hostal cielo azul
Exterior

Hostal cielo azul

2.0 star property
10.0 out of 10, Exceptional, (1)
"I traveled from Florida to Galapagos Island wirh my family, but they have a issue and Quito aereopuerto, that cause to me traveled by myself, but Im arrived to Isabella Island alone , the owner pick up me from muelle, and help me with everything, phone calls to call my family, safety place, thank you so much. If a have to put 100 star's I do , becouse you are exelent person and exelent plece to stay thank you so much. Tomy .🇺🇸🙏"
The price is AU$83
includes taxes & fees
1 Jan - 2 Jan 2025
Hostal cielo azul
Tiny house surrounded by a cedar forest!
Property grounds

Tiny house surrounded by a cedar forest!

10.0 out of 10, Exceptional, (1)
"Beautiful place with super accommodating host."
Tiny house surrounded by a cedar forest!
Suite con 2 Habitaciones
Outdoor pool

Suite con 2 Habitaciones

Suite con 2 Habitaciones
Casa Natura Galapagos Lodge
Outdoor pool

Casa Natura Galapagos Lodge

3.0 star property
7.2 out of 10, Good, (17)
"Great hotel in good location. If you like to be away from the busy town life and be in the thick of the out doors this is definitely the place to stay. Only draw back you have to keep catching a taxi which will cost you $5 each trip to get something to eat in the main town as there’s nothing near you. Only negative thing I can say about the hotel is they could improve on the breakfast. We stayed in quite a few boarding houses across Ecuador and the galapagos and this hotels breakfast was the...
Casa Natura Galapagos Lodge
Piedras Blancas Lodge
Outdoor pool

Piedras Blancas Lodge

2.5 star property
9.0 out of 10, Wonderful, (8)
"I like a lot the place! Very quiet and surrounded by nature. Rooms where perfectly clean and had a lot of space! We would like more options to eat, restaurant only opens for breakfast. Lunch and dinner has to be pre ordered. Beautiful place to relax"
Piedras Blancas Lodge
Hotel Quinta Margarita
Miscellaneous

Hotel Quinta Margarita

2.0 star property
Hotel Quinta Margarita
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Santiago Island
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Frequently asked questions

If I need to cancel my hotel reservation in Santiago Island, will I receive a refund?

Yes! Most hotel room reservations are fully refundable if you cancel before the hotel’s cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you booked a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of booking. Filter your search by free cancellation to find flexible hotel deals in Santiago Island.

What is staying in Santiago Island like?

Visitors can enjoy all that Santiago Island has to offer, including its parks. A top sight in the city is Galapagos National Park. Find out more about Santiago Island.

What are the top places to visit in Santiago Island?

The picturesque setting of Galapagos National Park and Mosquera Island exemplify the area's natural beauty. Additionally, you might want to add Puerto Egas to your itinerary. Take a look at what more there is to see and do in Expedia's Santiago Island guide.

What's the seasonal weather like in Santiago Island?

The hottest months are usually January and February, with an average temperature of 29°C, while the coldest months are August and September, with an average of 23°C. Average annual precipitation for Santiago Island is 598 mm.